Description

A Unified Theory that explains all Diseases

What if every disease — from cancer to infection to heart failure — shares a single underlying cause?

In What is Disease?, Dr. Rajkumar Chetty proposes a bold and sweeping answer: all human disease is, at its core, a failure of biological information. Drawing on Shannon Information Theory, systems biology and more than 35 years of clinical and pharmaceutical experience spanning four countries, Dr. Chetty reframes the entire landscape of medicine through a single unifying lens.

Rather than cataloging diseases in the traditional descriptive way, he reveals how cancer represents a breakdown in cellular cooperation, autoimmune disease resembles terrorism within the body’s own ranks, microbial infections are a form of biological warfare — and how every drug ever developed ultimately targets an information process.

This is not a textbook. It is a radical reconceptualization of what it means to be sick — and why the body sometimes loses the battle. Accessible yet intellectually rigorous, What is Disease? challenges doctors, researchers and curious readers alike to see human biology not as a collection of organs and symptoms, but as an exquisitely complex information system — one that disease disrupts and modern medicine strives to restore.

A Fellow of the Royal College of Pathologists and the Royal College of Physicians, Dr. Chetty brings rare authority to a genuinely original idea.